Associate Scientist – AAV Vectors - Molecular Biology

Associate Scientist – AAV Vectors - Molecular Biology

Job Title: Associate Scientist – AAV Vectors - Molecular Biology
Contract Type: Permanent
Location: Oxford
Salary: Up to £30,000 plus excellent benefits
Start Date: 2018-10-05
Reference: 15999 JH
Contact Name: James Hume
Contact Email:
Job Published: October 05, 2018 14:45

Job Description

James Hume is recruiting for an Associate Scientist AAV Vectors to join an ambitious company who are at the forefront of synthetic biology and its application to the discovery, development and manufacture of Biologics, Cell & Gene Therapies.  This role is to be part of their AAV Vector group that engineers viral vectors and novel bio – production methodologies working with both academia and industry.  An area that the company wants to continue to expand based on the demand for their expertise.  The purpose of this role is to support the generation of molecular constructs for AAV production.

Job Summary:
The Associate Scientist role is to support the generation of molecular constructs for the production of AAV vectors working with senior scientists and scientists.  This is a dynamic role where your attention will be divided between driving laboratory research forward using an innovative approach, project management and client communication.

The primary focus will be to use a range of molecular biology techniques to develop molecular constructs for the generation of AAV and their development up to production for use within R&D or clinical programmes.  As well as handling adherent cell lines using a range of technologies e.g. multiwell plates and hyperflasks.  Along with other lab based responsibilities such as leading the transfection of suspended cell lines and the application of analytical techniques for the genetic characterisation of viral particles.

This company has fantastic growth potential meaning there will be opportunities to further your career, and to contribute significantly in bringing new products and services to the market. Going forward you will be an important part as this function grows because this is a growth area for the company, meaning this role has very strong career progression opportunities. 

Desired Skills and Experience:
You will need to be educated to BSc or MSc in a relevant field such as Biology, Biochemistry, Genetics, Molecular and Cell Biology.  With commercial experience in a similar position using techniques that are transferrable to this role.  You will need to be familiar with AAV vectors and their genetics as well as the development of molecular constructs.  Additionally, you will need to have practical experience of molecular Biology techniques such as Ligations, restriction digestion, PCR, DNA sequencing, RT – PCR and ELISA.  As well as experience of cell culture and handling suspended and adherent cell lines.

The Company
The company are at the cutting edge of the use of Synthetic Biology to streamline the discovery, development and production of biologics, cell & gene therapies.  Their approach combines cutting edge use of bioinformatics taking advantage of algorithms and other tools that drive forward the rational designs of complex biological systems at the DNA level.  These are then assembled on their automated platform technology which enables them to develop systems for the discovery, engineering, and production of antibodies, viral vectors, packaging & production cell lines for lentivirus and AAV manufacture, CRISPR libraries and CRISPR engineering.  They intend to continue to build in the Viral Therapeutics field based on the capabilities of their technology and the demand for their Lentiviral, AAV and Adenoviral vectors.

They are going through a continued period of expansion due to the demand of their services from industry as well as after entering some major longstanding partnerships.  In addition to this they have other technologies under development after securing funding that will further enhance the portfolio of services they can offer.   They have an excellent culture where staff are all working closely together with the opportunity of rapid promotion as part of their culture and provide the chance to learn new skills.  In addition to the career path they are conscious of the work team members put in and because of this arrange regular events outside of work, away days and other events internally.

In addition to a competitive salary, the company offers an excellent benefits package including: 

  • 25 days Annual Leave plus Bank Holidays
  • Pension with matched employer contribution to 7%
  • Health Insurance
  • Group Life Cover
  • Child Care Voucher Scheme
  • Glasses Vouchers
  • Modern, welcoming working environment