Scientist - Viral Vectors

Scientist - Viral Vectors

Job Title: Scientist - Viral Vectors
Contract Type: Permanent
Location: London
Salary: up to £38,000 plus bonus and benefits package
Start Date: 2019-07-23
Reference: 16307 JH
Contact Name: James Hume
Contact Email:
Job Published: July 24, 2019 15:04

Job Description

A biotech based on central London who at the cutting edge of research into cell & gene therapies are recruiting for another Viral Vector Scientist due to demand for their expertise.  This role is within their industrialisation group with the responsibility for developing bioprocessing techniques for the manufacture of vectors for use in clinical trials.
The company are a centre of excellence with the purpose to advance and accelerate the growth and development of the UK Cell & Gene Therapy sector.  They do this by collaborating with both academia and industry to take innovative therapies successfully across the translational gap to the clinic and then through clinical trials to launch.  They offer leading edge capabilities in process development, manufacturing in their state-of-the-art laboratories as well as expertise in regulatory, clinical, market access and health economics.  Their long-term objective is to make the UK the place to come to commercialise therapies, by being the most compelling choice to their international partners.  They do not have a set therapeutic area, but a large part of their focus is on immuno– oncology programmes.  They work in a very and dynamic forward-thinking way looking to utlise the latest technologies enable them to remain at the forefront of research into this exciting sector that has great potential.
Role Summary:  The purpose of the Viral Vector Scientist is to use QBD principals for the design of experimental programmes working closely with collaborators throughout projects and mentoring more junior scientists.  The purpose of the research is the process development of vectors (AAV, retroviral and lentiviral) for clinical trial manufacture using commercial bioprocessing techniques such as stirred tank bioreactors, filtration processes for primary recovery, chromatographic purification methods such as AKTA. 
As a Scientist, you will be working with Lead Scientists to contribute to the design of process development activities for the projects, working on several at a time.  With the responsibility for mentoring more junior scientist in their day to day work.  With the added responsibility for maintaining compliance as well as directly liaising with collaborators throughout the lifecycle of projects.  This is to give you the grounding to develop your career further as they continue to grow.
Desired Skills and Competencies: As a Scientist, you will need to have a PhD or MSc with commercial experience of upstream and / or downstream bioprocessing of viral vectors e.g. lentiviral, retroviral, lentiviral.  It does not have to be all of these as you can be cross trained on others.  If you have GMP experience of the manufacture of vectors or similar therapies or biologics this is advantageous to your application. Cell culture of mammalian or human cells is essential along with experience of using bioreactors.  Experience of using AKTA technology or other chromatographic techniques is essential for this opportunity.