A biotech at the cutting edge of gene therapy research is recruiting for a Scientist with experience of developing viral vectors to join their expanding Process Development team. The team is part of their Industrialisation Group who are developing manufacturing processes for viral vectors as part of translational research. As a Viral Vector Scientist, you will help design, execute, and document process development projects to create scalable processes for the manufacture in clinical trials.
As a Scientist, you will be contributing the design of experimental programmes using QBD principals to help design, execute, document and deliver Viral Vector scale up projects. They work with a range of vectors such as Lentiviral, AAV, Adenoviral and Retroviral vectors, however you do not need experience of all 3. Using methods such as primary recovery filtration approaches, purification via chromatographic methods, and analytical techniques. As well as cell factory-based expansion and stirred tank bioreactor processing to develop upstream and downstream methods.
As this is a more senior position within the laboratories you will be working closely with senior members of the team to manage projects and you will often be working autonomously. You will be a point of contact for collaborators during the project plus other responsibilities e.g. keep up to date with the latest industry developments and be part of academic and knowledge sharing groups.
This role comes with excellent career progression as they have a strong career development programme enabling you to take the direction you want as they grow and expand as a company.
Desired Skills and Competencies:
As a Scientist, you will need to have a PhD or MSc with commercial experience of upstream and / or downstream bioprocessing of viral vectors, biologics, cell or gene therapies. You do not need experience of working with all 3 vector types listed but at least 1 is essential. If you have GMP experience of the manufacture of therapies or biologics or vectors this is advantageous to your application but not essential. Cell culture of mammalian or human cells is essential along with experience of using bioreactors. Experience of using AKTA technology or other chromatographic techniques is advantageous for this opportunity.
The company are a centre of excellence with the purpose to advance and accelerate the growth and development of the UK Cell & Gene Therapy sector. They do this by collaborating with both academia and industry to take innovative therapies successfully across the translational gap to the clinic and then through clinical trials to launch. They offer leading edge capabilities in process development, manufacturing in their state of the art laboratories as well as expertise in regulatory, clinical, market access and health economics. Their long-term objective is to make the UK the place to come to commercialise therapies, by being the most compelling choice to their international partners. They do not have a set therapeutic area but a large part of their focus is on immuno– oncology programmes. They work in a very and dynamic forward thinking way looking to utlise the latest technologies enable them to remain at the forefront of research into this exciting sector that has great potential.