Senior Scientist - Process Development

Senior Scientist - Process Development

Job Title: Senior Scientist - Process Development
Contract Type: Permanent
Location: Stevenage
Salary: £40000 - £50000 per annum, Benefits: Excellent Benefits
Start Date: 2020-01-10
Reference: V-46025
Contact Name: James Hume
Contact Email:
Job Published: January 10, 2020 11:48

Job Description

A clinical stage Cell Therapy company who are developing a unique and personalised approach to curing cancer are recruiting for a Senior Scientist to join the Research & Development team to be based at their Stevenage laboratories.  As a company they are developing personalised cell therapies for the treatment of lung cancer and melanoma and have therapies entering the clinic complemented by an expanding translational pipeline. 

This Senior Scientist will be within their Process Development team to focus on the development of their next generation of T Cell Therapy products.  As a Senior Scientist you will be setting out the strategies for process development to then execute and oversee experimental programmes. 

As a Senior member of the team you will work with the Group Leader to design programmes to support the development of novel processes to expand reactive neoantigen cells.  Once in place you will execute these including working with more junior colleagues by providing them with direction and mentorship with their support for bench work.  In this role you will also design, validate and run functional immunoassays for the characterisation of your work.  This is an advanced environment where you will be working closely with their Bioinformatics team and their Clinical Operations too. 

This is an opportunity where you will gain exposure to not just cutting-edge technology that has the potential to transform the management of cancer.  But also, a wide range of responsibilities to prepare you for promotion to more senior or technical roles depending on how you want your career to develop. 

Desired Skills and Competencies:

For this opportunity, you will need to be educated to PhD with expertise in a relevant area such as immunology, oncology etc.  With expertise in small- and large-scale immune cell isolation, cell culture, and T cell functional assays.  You will need to have experience of using flow cytometry and high flow data analysis.  You will need to have a strong knowledge of cancer immunology for this role.  If you have experience of working with tissue and patient blood samples this is advantageous to your application.  

The Company: 

The company are developing an approach to curing cancer that is different and enables them to meet unmet needs.  They are developing novel immunotherapies that are targeting the protein markers that are unique to each person and expressed on the surface of each cancer cell.  These are called Neoantigens and their approach is to sequencing data from each patient sample in conjunction with their bioinformatics platform to identify and then develop a cell therapy to target the neoantigens.  This way a personalised treatment can be developed that targets only cancer cells not healthy tissue and destroy the tumours.