Senior Viral Vector Scientist - Downstream Processing

Senior Viral Vector Scientist - Downstream Processing

Job Title: Senior Viral Vector Scientist - Downstream Processing
Contract Type: Permanent
Location: Central London
Salary: £40000 - £50000 per annum, Benefits: bonus, pension, life insurance, health insurance and 28 day holidays
Start Date: 2020-09-22
Reference: V-46386
Contact Name: James Hume
Contact Email:
Job Published: September 23, 2020 10:59

Job Description

A pioneering company who are at the centre of the Cell & Gene Therapy sector are seeking a Senior Scientist with experience of Downstream Processing to join their Viral Vector development Group based in Central London.   They are recruiting for a Senior Scientist with a background in the Downstream Processing of Viral Vectors and the use of chromatography with additional experience of Tech Transfer.


They collaborate with academia & industry, providing their expertise to take therapies across the translational gap, into the clinic and the through clinical trials. The company’s mission is to drive its growth of the sector to ensure these therapies are commericalised and have an international presence with projects coming from UK, Europe, US and Asia.  Taking an innovative approach to develop and adopt the latest technologies to keep them are the forefront of the sector.


The Role of Senior Scientist:


As a Senior Scientist you will be providing leadership in the laboratories with responsibility for directing more junior colleagues and driving project forwards to deliver these on time.  But crucially have influence on the design of projects, design experimental programmes and use your science.  The projects will be focused on the Downstream processing of Viral Vectors, in particular AAV, for the development of GMP ready manufacturing protocols using closed systems.


Responsibilities includes:


  • Contribute to the design of Downstream projects, working with the Director and Lead Scientists to establish these
  • Managing multiple projects in the laboratory, driving these forwards to deliver these on time
  • Use your knowledge of Viral Vector process and analytical development to develop experimental programmes and then execute these.
  • Focus on DSP, chromatography, and purification techniques
  • Tech transfer of processes into and out of the laboratories
  • Work with Lead Scientists and Programme managers to support pricing and planning of proposals for potential collaborators
  • Support Business Development during the scoping of new projects.
  • Take responsibility for the quality & standards of research
This is an excellent opportunity where you will be able to apply your science in an innovative environment at the cutting edge for develop of Cell & Gene Therapies with excellent career potential.


Required Skills and Expertise:


  • BSc in relevant area is essential, an MSc or PhD is desirable
  • Downstream Processing of Viral Vectors in a GMP or GMP ready environment
  • Tech Transfer experience is desirable
  • Chromatography experience e.g. AKTA is essential
  • Cell culture of human and / or mammalian cell lines essential


Company Overview:


The company’s aim is to advance the cell & gene therapy sector to make the UK the place to commercialise these life changing therapies.  They have the capabilities to take a therapy from the discovery phases, across the translational gap to the clinic and then through clinical trials to launch.  Using their R&D expertise to achieve this along with their drive for innovation and continuously adopting the latest and most effective approaches.  To completement their R&D efforts they have world class clinical operations, regulatory, health economics and market access expertise.  Added to this they have developed a unique and highly successful GMP manufacturing facility based in Stevenage where collaborators can manufacture their therapies for clinical trial and commercial use.


They have a strong culture that is focused on collaborative and innovative working to deliver these life changing therapies to patients.  As a company they offer excellent career development opportunities through their L&D programme that not only gives you the skills to advance your career but creates opportunities to take the step forwards to utilise them in a new position.  Added to this they are continuing to expand as the demand for their expertise increases and they explore new areas of the sector.