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Expired
  • Location: Edinburgh, EH259RG
  • Salary: Competitive salary and benefits package - details to be disclosed upon application.
  • Job Type:Permanent

Posted almost 3 years ago

  • Sector: Scientific Development
  • Contact: Aaron Stone
  • Contact Email: aaron.stone@nextphaserecruitment.com
  • Contact Phone: 01403 216216
  • Start Date: 2021-06-21
  • Job Ref: V-46896
Director of Cell Line Development required for a world leading gene therapy company based near Edinburgh. The Director of Cell Line Development will be responsible for leading the expanding team of research scientists engineering the proprietary cell line and next generation stable producer cell line for AAV production for optimum yield and quality and subsequent transfer into process development and cGMP manufacturing.

The ideal candidate will have a comprehensive understanding of cellular biology and cell line development. Individuals with specific experience and detailed knowledge of AAV would be of significant interest. 

On offer is a highly competitive salary which can be disclosed upon application. The package will include up to a 20% bonus, LTIP of up to $365k which will be paid out after certain milestones are met (predicted timeframe of 4-6 years) and contributed pension. This candidate may also be eligible for a relocation package if they are relocating to the area.

Skills and responsibilities of the Director of Cell Line Development:
  • Expected to contribute significantly to the direction of the cell line engineering team, designing overall strategy and ensuring implementation.
  • Have a strong molecular biology understanding.
  • Have an appreciation of the impact of non-coding RNA on bioprocesses and biological functions.
  • Significant experience and understanding of gene editing tools, CRISPR, Cre-recombinase, etc. for the generation of cell lines.
  • Understand and adhere to the requirements for generating a cell line for cGMP manufacturing. Communicate effectively in technical transfer to the process development team.
Management responsibility of the Director of Cell Line Development:
  • You will be expected to directly manage a growing team of scientists and senior scientists, setting goals and objectives and ensure the delivery of projects on time.
  • Lab management, ensuring appropriate levels of control over scientific data, equipment, and materials, maintaining appropriate levels of documentation, record keeping, and procedures.
  • Interact with senior members of the research team to ensure appropriate experimental design and analysis.
  • Collaborate with the international team.
Experience and skillset required:
  • The ideal candidate will be Ph.D. qualified with several years of demonstrable industry experience in cell line development and ideally from within a Cell & Gene Therapy environment.
  • You will be an accomplished leader, with strong team-building skills and the ability to collaborate and deliver across multi-disciplinary projects.
  • Innovative and natural problem solver; able to “join the dots” of disparate information.
  • Confident and clear presentation of data, verbally and through written reports.