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Expired
  • Location: Cambridge
  • Salary: Competitive
  • Job Type:Permanent

Posted about 3 years ago

  • Sector: Clinical Operations
  • Contact: James Hume
  • Contact Email: james.hume@nextphaserecruitment.com
  • Contact Phone: 01403 216216
  • Start Date: 2021-01-22
  • Job Ref: V-46611

Summary:

This is an influential Senior Scientist opportunity where you will be responsible for driving R&D programmes forwards in the laboratory. With a focus on the development and validation of new iPSC neurons e.g. astrocytes from human sources.  You will be leading projects in the laboratories with the opportunity to manage a small team.



The company:

They are based in Cambridge and their step change technology that is a combination of stem cell biology and synthetic biology. The purpose of this is to accelerate the discovery, development, and manufacture of cell therapies through the control of synthetic biology circuits.

Their aim is to build a scalable model that enables the production of cells that are actually affected by the targeted disease and accelerate the development of cures.  Their focus is currently on human induced Neurological and Skeletal stem cells.

They received significant funding to complement their own plans which has led to a rapid expansion as they meet their current aims and work towards the development of new ideas.



The Role of Senior Scientist:

As a Senior Scientist you will be leading R&D projects as well as the possibility of a team with the responsibility for the design, and execution of reprogramming strategies to obtain human iPSC derived glia cells.

      • Supervising more junior scientists to ensure projects are delivered on time.

      • Working with external partners to develop and characterise new cell lines and disease modles.

      • Collaborative working with other teams such as Project Management, Product Development to meet product launch timelines.

      • Working with senior group members to develop proposals across differing stages of the pipeline.

Your Expertise:


For this opportunity you will need to have:

  • A PhD in stem cells or neurobiology or related area

  • Post-Doctoral OR Commercial Experience

  • Experience of developing iPSC derived glia cells in academia or industry

  • Knowledge of the molecular mechanisms for the definition of cellular identities in the CNS

  • Use of iPSC derived glia cells in disease modelling.

  • Ability to culture Pluripotent Stem Cells, iPSC derived glia cells – e.g. astrocytes

  • Expertise in the development and use of Characterisation Assays.

  • Supervisory or Mentorship experience