- Job Title: Lead Scientist – Commercialisation
- Salary: Up to £55,000 dependent on experience, plus excellent benefits (bonus, pension (10% company contribution), private medical cover, life assurance plus others)
- Location: Central London
- Senior Strategic Position with the Responsibility for Managing a Small Team of Scientists Commercialising Novel Cell & Gene Therapies
- Developing the Experimental Programmes to be Executed and the Creation of Longer Term Strategies that will Impact on the Development of Therapies in this Fast Developing Sector
James Hume is recruiting for a Lead Scientist who has experience of the commericalisation process for cell and gene therapies, in particular crossing the translational gap into clinical trial manufacture, to join a Biotech based in Central London. They need a creative scientist to lead a team who are developing the next generation of therapies, taking these through the process, analytical and manufacturing stages to clinical trial manufacture.
The company are at the cutting edge of research into Cell and Gene therapies, working with their partners to take these through the commercialisation process to market launch. So far they have successfully taken therapies to phase II clinical trials with these progressing to phase III soon. Which has led to the construction of a new manufacturing facility to meet the increased volume of therapies needed for the latter stages of clinical trials. They not only have therapies under development across a wide range of therapeutic areas including oncology and cardiovascular. They are also researching into advanced manufacturing processes such as automation, developing characterisation of potency assays, cell plasticity projects, sterility testing alongside their therapy development programmes to support the growth of the sector. They work in a very and dynamic forward thinking way looking to utlise the latest technologies enable them to remain at the forefront of research into this exciting sector that has great potential.
This is a senior role that has a strong strategic element to complement the day to day management of a small team within the wider commercialisation group. The purpose of the role is to use your scientific and sector knowledge to leadership within the analytical development, process development and manufacturing laboratories. With the responsibility for the design of experimental programmes you are working on, then overseeing these in the laboratories on a day to day basis to deliver results to meet deadlines and milestones.
To deliver the purpose of the position you will maintain up to date knowledge of the cell & gene therapy sector, and utlise this knowledge to develop strategies to be employed within the wider team to support the delivery of the company’s goals. As a Lead Scientist you will contribute to the scouting of developmental programmes to support the wider sector. On a day to day basis you will ensure your team are working to the best of their capabilities to deliver results on time whilst operating in compliance to regulations and in a collaborative manner internally and externally.
Desired Skills and Competencies:
You will need to have the ability to lead teams of scientists to not only successfully deliver projects but also maintain compliance of their work. But also motivate them and support their development to help further progress their careers.
As a Lead Scientist you will need to have a strong knowledge of the sector and its landscape and the impact of strategic development goals for process and analytical development. On a technical basis you will need to be skilled in molecular and protein based analytical techniques such as PCY, cytotoxicity assays and cell based functional assays. Plus mammalian and human cell culture expansion methodologies with experience of downstream processes. Ideally educated to PhD level but more important is the relevant technical and sector knowledge relating to the commercialisation of cell and gene therapies.
Project Manager, GMP, clinical trials, monitoring, GCP, cell therapy, novel therapy, gene therapy, NHS, budget, IP, intellectual property, negotiate, collaboration, programme, programme manager, CMO, CRO, milestone, delivery, clinical trials, supply chain, methodologies, innovation, regenerative medicine, collaborate, plans, development, R&D, research and development, transactions, contract, milestone, acquisition, legal, structure, budget, biotech, biopharmaceutical cell therapy, gene therapy, process development, autologous, analytical development, manufacture, HTA, RT-qPCR, ELISA, process optimisation, cytotoxicity, QMS, GMP, automation, cell culture.