Process Development Scientist

Process Development Scientist

Job Title: Process Development Scientist
Contract Type: Permanent
Location: Central London
Salary: £34,000 to £38,000 + Excellent Benefits
Start Date: ASAP
Reference: 15767 JH
Contact Name: James Hume
Contact Email:
Job Published: February 09, 2018 17:24

Job Description

James Hume is currently recruiting for a Process Development Scientist with experience of Immunology to join a centre of excellence who are leading the way in the development of cell & gene therapies.   By providing the multi - disciplinary expertise needed to bring these to the market.  Their R&D Laboratories are in Central London, where this role will be based, and its purpose is to support the development of  therapies to develop scalable clinical manufacturing protocols to eventually become suitable for commercial use.

The Company:

The company are a centre of excellence that is at the forefront of creating a viable and sustainable cell and gene therapy industry in the UK.  Their headquarters are in central London where they have built a market leading multidisciplinary team that has the ability to take a therapy from concept through the development cycle to the market.  They collaborate with both academia and industry and they are able to provide the scientific, clinical and commercial expertise needed to overcome the challenges that hinder the commercialisation of these fast developing, cutting edge technologies.  Their longer term aim is to make the UK a global leader in the development and commercial exploitation of therapies.  They are making great strides towards this aim with therapies entering phase 2 clinical trials and building credible cases to be progressed to stage 3.  Added to this they are expanding their manufacturing and development operations to meet increased demand for their services from the academic and commercial sectors.

The Opportunity:

The Process Development Scientist role is within their R&D laboratories where you will use sate of the art tools to identify the process that will result in scalable manufacturing protocols.  Developing the processes to take novel therapies from research scale to a level suitable for clinical manufacture and ultimately commercial level.  To also support the development of experiments to implement process improvements across a range of developmental programmes using your science to do so. 

This is in fact a relatively senior position within the laboratories with responsibility to design the experimental programmes with Senior Scientists and then manage these within the laboratories.  Then managing these throughout their lifecycle to ultimately deliver results by working closely with technicians who will support you in these, using your science to overcome any issues faced. 

This is a broad and challenging role where you will be able to use your science to overcome the hurdles faced in the commercialisation of cutting edge technologies.  You will be working on a number of programmes at a time in an innovative, collaborative and flexible environment.

Desired Skills and Competencies:

Due to the nature of the Process Development team being multi-disciplinary which is due the range of projects the company are working on needing different skill sets means need to have at least 2 of the following as well as a relevant PhD or MSc combined with commercial experience:


  • Experience of Technology Transfer
  • Experience of Immunology
  • Experience of Immune Cell Processing Technologies e.g. primary cell isolation, cell activation transduction and transduction
  • Experience of processing technologies including bioreactor, cell separation, and formulation technologies.
  • Experience of Allogenic cell processing, e.g. pluripotent stem cell expansion, differentiation and quality analysis
  • Experience of automated cell processing technologies
  • Experience of transfer to GMP manufacture
  • Knowledge of cell culture analysis e.g. flow cytometry, and FACS sorting

Due to the broad nature of the role and skill sets please write a cover letter to enhance your application by highlighting what relevant skills you have and the environments you have used them in.