Principal Formulation Chemist
Principal Formulation Chemists lead the design and development of pharmaceutical formulations that optimize the delivery, stability, and bioavailability of active pharmaceutical ingredients (APIs). They oversee pre-formulation studies, develop new drug delivery systems, and guide products through scale-up and tech transfer.
Key responsibilities:
Designing dosage forms – Including tablets, capsules, suspensions, injectables, or inhalables tailored to the physicochemical properties of the API.
Conducting compatibility and stability studies – Using analytical methods like HPLC, DSC, and particle sizing to evaluate formulation performance over time.
Guiding scale-up and GMP manufacturing – Working with process engineers and quality teams to ensure reproducibility and regulatory readiness.
Leading formulation strategy – Including QbD approaches, DoE experimental planning, and documentation for regulatory submissions (e.g. IND, NDA, MA).
Mentoring formulation scientists – Providing scientific and strategic leadership to support R&D milestones and client projects.
This role typically requires experience with excipients, granulation, lyophilization, and other pharmaceutical manufacturing techniques, along with strong knowledge of ICH, FDA, and EMA expectations.
East Sussex
East Sussex is a county in south East England to the south of London and bordered by the English Channel to the south. Major towns in East Sussex include Brighton and Hove, Lewes, Eastbourne, Rye and Hastings. Transport links in East Sussex are not particularly good as there are no motorways, but this doesn’t stop thousands of people visiting the beautiful coastline, rolling countryside and cosmopolitan Brighton, which means that the tourism industry is a major employer in this area. Other industries that are prominent in East Sussex include Pharmaceuticals, low carbon technologies, publishing, web & app design and Medical Communications. The otherwise quiet town of Lewes hosts the largest bonfire Night celebrations in the UK during which burning crosses and effigies are paraded through the town by 7 separate bonfire societies, watched by crowds of up to 80,000.
East Sussex has a School of Life Science which is a diverse, collaborative community with expertise in areas as varied as cancer biology, drug discovery, neurosciene and biodiversity. The University of Sussex is a leading research-intensive university near Brighton. We have both an international and local outlook, with staff and students from more than 100 countries and frequent engagement in community activities and services.
East Sussex has a small but growing life sciences and healthcare cluster of companies specialising in the research, development and manufacture of medical devices, biotechnology, poharmaceutical products and preparations and natural science and engineering research.
Daval International Ltd in Eastbourne focuses on the development and delivery of new treatments for neuro-degenerative, inflammatory and autoimmune diseases.
Companies also supply specialist services and instruments for life science labs and biotechnology industries. These include temperature monitoring systems (QCBug) and bespoke software solutions (Biomedical Computing Ltd).
Famous people born in East Sussex: Jo Brand, comedienne and Katie Price, “celebrity”
East Sussex is a great place to further your career in life sciences. If you are a looking for pharmaceutical jobs in East Sussex, scientific careers in East Sussex or want to discuss cell therapy, gene therapy, ATMP, medical device, technology, biotech or pharmaceutical job opportunities in East Sussex, give our Next Phase team a call. The East Sussex area is continuing to expand as a centre for jobs in science, process development, technology, software development, project management, informatics, quality, reg affairs and supply chain.
At Next Phase we help people find new jobs in life sciences across the UK, Europe and USA. This page lists some of the job opportunities in East Sussex, and if you give us a call we can also talk to you about other scientific jobs, pharmaceutical career opportunities and the latest updates in cell and gene therapy and ATMP development in the East Sussex area.
