Principal Formulation Chemist Sandwich

Principal Formulation Chemist

Principal Formulation Chemists lead the design and development of pharmaceutical formulations that optimize the delivery, stability, and bioavailability of active pharmaceutical ingredients (APIs). They oversee pre-formulation studies, develop new drug delivery systems, and guide products through scale-up and tech transfer.

Key responsibilities:

• Designing dosage forms – Including tablets, capsules, suspensions, injectables, or inhalables tailored to the physicochemical properties of the API.

• Conducting compatibility and stability studies – Using analytical methods like HPLC, DSC, and particle sizing to evaluate formulation performance over time.

• Guiding scale-up and GMP manufacturing – Working with process engineers and quality teams to ensure reproducibility and regulatory readiness.

• Leading formulation strategy – Including QbD approaches, DoE experimental planning, and documentation for regulatory submissions (e.g. IND, NDA, MA).

• Mentoring formulation scientists – Providing scientific and strategic leadership to support R&D milestones and client projects.

This role typically requires experience with excipients, granulation, lyophilization, and other pharmaceutical manufacturing techniques, along with strong knowledge of ICH, FDA, and EMA expectations.​

Sandwich

Sandwich is a town in the east of Kent in the South East region of England.  Other towns and cities close to Sandwich include Canterbury, Ashford, Dover, Ramsgate and the revitalised resort town of Margate.  The name of the town is probably of Saxon derivation meaning a “sandy place” rather than the well-known lunchtime food item.  It is thought that the term “sandwich” came about when the 4^th Earl of Sandwich asked for his lunchtime meat to be served between slices of bread so that he did not have to interrupt his gambling for lunch!  Sandwich was one of the Cinque Ports which was a confederation maritime towns and villages in Kent and East Sussex dating back 1000 years that supplied fleet, military and transport services to the Monarchy prior to the creation of the Royal Navy.   Although it was a major port in bygone days, Sandwich is now two miles from the sea and the reclaimed land is home to nature reserves and golf courses including Royal St George’s.

Pfizer, the multinational pharmaceuticals company, is a major employer in Sandwich and many well-known drugs including Viagra were developed in their laboratories in Sandwich.  In addition to Pfizer, Discovery Park in Sandwich, the leading science park in Kent, is home to numerous Life Science, Biotech, Technology and R & D companies which employ a total of 3000 staff.