Principal Formulation Chemist Wales

Principal Formulation Chemist

Principal Formulation Chemists lead the design and development of pharmaceutical formulations that optimize the delivery, stability, and bioavailability of active pharmaceutical ingredients (APIs). They oversee pre-formulation studies, develop new drug delivery systems, and guide products through scale-up and tech transfer.

Key responsibilities:

• Designing dosage forms – Including tablets, capsules, suspensions, injectables, or inhalables tailored to the physicochemical properties of the API.

• Conducting compatibility and stability studies – Using analytical methods like HPLC, DSC, and particle sizing to evaluate formulation performance over time.

• Guiding scale-up and GMP manufacturing – Working with process engineers and quality teams to ensure reproducibility and regulatory readiness.

• Leading formulation strategy – Including QbD approaches, DoE experimental planning, and documentation for regulatory submissions (e.g. IND, NDA, MA).

• Mentoring formulation scientists – Providing scientific and strategic leadership to support R&D milestones and client projects.

This role typically requires experience with excipients, granulation, lyophilization, and other pharmaceutical manufacturing techniques, along with strong knowledge of ICH, FDA, and EMA expectations.​

Wales has become home to some of the world’s most progressive companies within the Life Sciences industry. The sector has developed into established clusters of excellence in high-growth markets including, in vitro diagnostic, single use technology and Wound care.

Medical technology companies in Wales vary from large corporate multinationals (including Thermo Fisher Scientific and Zimmer/Biomet) to smaller start-ups built around innovation arising from the Welsh academic research base such as MedaPhor and Cyden.

Wales can boast some world leading anchor companies. Employment in the Welsh medical technology sector is dominated by significant and leading enterprises, such as GE Healthcare, Siemens Healthcare, Thermo Fisher Scientific and Zimmer Biomet.

Their eight universities are home to over 160,000 students, 12,000 of these in Life Sciences, and take part in a wide range of research and technology projects offering meaningful partnering opportunities for Life Sciences businesses.

Wales is a great place to further your career in life sciences. If you are a looking for pharmaceutical jobs in Wales, scientific careers in Wales or want to discuss cell therapy, gene therapy, ATMP, medical device, technology, biotech or pharmaceutical job opportunities in Wales, give our Next Phase team a call. The Welsh area is continuing to expand as a centre for jobs in science, process development, technology, software development, project management, informatics, quality, reg affairs and supply chain.

At Next Phase we help people find new jobs in life sciences across the UK, Europe and USA. This page lists some of the job opportunities in the UK, and if you give us a call we can also talk to you about other scientific jobs, pharmaceutical career opportunities and the latest updates in cell and gene therapy and ATMP development in the area.

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