Principal Formulation Chemist
Principal Formulation Chemists lead the design and development of pharmaceutical formulations that optimize the delivery, stability, and bioavailability of active pharmaceutical ingredients (APIs). They oversee pre-formulation studies, develop new drug delivery systems, and guide products through scale-up and tech transfer.
Key responsibilities:
Designing dosage forms – Including tablets, capsules, suspensions, injectables, or inhalables tailored to the physicochemical properties of the API.
Conducting compatibility and stability studies – Using analytical methods like HPLC, DSC, and particle sizing to evaluate formulation performance over time.
Guiding scale-up and GMP manufacturing – Working with process engineers and quality teams to ensure reproducibility and regulatory readiness.
Leading formulation strategy – Including QbD approaches, DoE experimental planning, and documentation for regulatory submissions (e.g. IND, NDA, MA).
Mentoring formulation scientists – Providing scientific and strategic leadership to support R&D milestones and client projects.
This role typically requires experience with excipients, granulation, lyophilization, and other pharmaceutical manufacturing techniques, along with strong knowledge of ICH, FDA, and EMA expectations.
West Sussex
West Sussex is a county on the south coast of England and over many centuries the strategic location of West Sussex has played a key part in history, defence and trade. West Sussex offers a wealth of interesting places to visit from historic West Sussex towns and cities such as Chichester, Arundel and Petworth to West Sussex coastal resorts including Worthing and Bognor Regis. A substantial part of the South Downs National Park is also located in West Sussex as are many West Sussex nature reserves and areas of outstanding natural beauty. West Sussex is also a great place to live and work, with a wide range of West Sussex industries and West Sussex businesses established in towns such as Crawley, Horsham, Haywards Heath and Burgess Hill to the north of the county. Gatwick airport, one of the busiest in Europe, is a further benefit to businesses, residents and international visitors to West Sussex.
Famous people born in West Sussex: Harry Enfield, comedian and Percy Bysshe Shelley, poet, also born in West Sussex.
From world-renowned Medical and Diagnostic Technology companies, to major Pharmaceuticals and Industry Support services, West Sussex's Health and Life Sciences Cluster is booming. The country is home to over 90 diverse companies, contributing to the forefront of innovation in the Global Health and Life Sciences sector. A strong cluster has emerged in the county with collaboration between businesses, research and public health, facilitated by WSCC who is investing heavily in the growth of the sector. West Sussex provides a highly attractive offer for global and national businesses wanting to be in the forefront of innovation, in the heart of growth.
West Sussex is a great place to further your career in life sciences. If you are a looking for pharmaceutical jobs in West Sussex, scientific careers in West Sussex or want to discuss cell therapy, gene therapy, ATMP, medical device, technology, biotech or pharmaceutical job opportunities in West Sussex, give our Next Phase team a call. The West Sussex area is continuing to expand as a centre for jobs in science, process development, technology, software development, project management, informatics, quality, reg affairs and supply chain.
At Next Phase we help people find new jobs in life sciences across the UK, Europe and USA. This page lists some of the job opportunities in West Sussex, and if you give us a call we can also talk to you about other scientific jobs, pharmaceutical career opportunities and the latest updates in cell and gene therapy and ATMP development in the West Sussex area.
