Senior Scientist II, PD Vector – Upstream Cambridgeshire

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Cambridgeshire

Cambridgeshire is county in the East of England region.  Major towns and cities in Cambridgeshire include Cambridge, Peterborough and Huntingdon.  Most of Cambridgeshire is agricultural.  However, recent years have witnessed the rapid growth of a large cluster of high-tech electronics, IT, software and biotechnology businesses setting up in the area, so much so that it is now referred to as “Silicon Fen”.   Many of these high-tech businesses have grown up around the world famous Cambridge University, which is frequently ranked as one of the top universities in the world.  The city of Cambridge with its stunning architecture, museums and riverside location is a popular tourist destination.                                                                 

Famous people born in Cambridgeshire:  Clive Woodward, World Cup winning England rugby coach and Olivia Newton-John, singer