Senior Scientist II, PD Vector – Upstream Greenford

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Greenford

Greenford is located in the London Borough of Ealing in north west London.  Towns and suburbs close to Greenford include Harrow, Brentford, Hayes, Watford and Slough.  Greenford is on the Central Line of the London Underground and also has overground rail connections into central London.  Road connections are also good as Greenford is located on the A40 which leas out to the M40 and then onto the M25, Heathrow Airport is on 12 miles away.  Greenford is well-located for a number of leisure-time places of interest including the world-famous Wembley Stadium and Wembley Arena, both of which are only 3 miles away.   Two excellent museums are also in the Greenford area; the London Motorcycle Museum, which has a wide range of bikes & memorabilia on display, and the Musical Museum which has a huge collection of self-playing musical instruments ranging from very small clockwork music boxes to huge “Mighty Wurlitzer” organs.   

Famous people from Greenford: Jourdan Dunn, model and Steven Warner, actor