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Automation Scientist - Cell Processing

Automation Scientist - Cell Processing

Job title: Automation Scientist - Cell Processing
Contract type: Permanent
Location: Cambridge
Sector:
Salary: Competitive
Start date: 2021-02-11
Reference: V-46637
Contact name: James Hume
Contact email: james.hume@nextphaserecruitment.com
Published: 14 days ago

Job Description

Summary:

This is an influential Scientist opportunity in a role where you will have a dual focus.  Firstly, you will be involved in internal and external R&D programmes to design, build and implement bespoke automation platforms. Secondly, to ensure all equipment is available and being maximized using your technical and software capabilities.  They use automated systems such as Hamilton, Satorious, and Tecan for example.

 The company: 

They are based in Cambridge and their step change technology that is a combination of stem cell biology and synthetic biology.  The purpose of this is to accelerate the discovery, development, and manufacture of cell therapies through the control of synthetic biology circuits.

Their aim is to build a scalable model that enables the production of cells that are actually affected by the targeted disease and accelerate the development of cures.  Their focus is currently on human induced Neurological and Skeletal stem cells.

They received significant funding to complement their own plans which has led to a rapid expansion as they meet their current aims and work towards the development of new ideas.

 

The Role of Automation Scientist:

As an Automation Scientist you will be contributing to the design and then leading the execution of R&D projects as well as ensuring equipment is utlised to maximum capacity. With a focus on both R&D programmes and day to day equipment such as Hamilton robots.  The purpose of this research is to deliver process improvement, scale up, and automation processes for the manufacture of iPSC derived cell types.  To achieve this, you will be working with a diverse range of teams including IPSC Manufacturing Development, Quality, Production and Business Analysts.   

 

  • Supervise the implementation and validation of new automated systems.
  • Work collaboratively with system users to develop SOP’s, assy protocols for automation and ensure optimal efficiency and performance.
  • Establish key criteria for scale up & automation including process validation.  (CPP, CQA etc.)
  • Optmise, validate and troubleshoot high throughput workflows.
  • Contribute to equipment deep dive activities and root cause analysis activities.
  • Train users in systems and their use to ensure best practice is followed.
  • Identify current and future resource requirements in people and systems and lead recruitment in a rapidly growing company.
 

Your Expertise:

 For this opportunity you will need to have:

  • A degree or higher qualification in Biology, molecular biology, automation, or similar field
  • Experience of working in an automated environment e.g., Hamilton, Tecan, Sartorius
  • Experience of working with cell lines, stems cells or iPSC’s.
  • Developing and optimizing complex protocols for liquid handling automation – cell line expansion, differentiation, and cryopreservation.
  • Experience at using programming languages.
  • Experience of developing, optimizing, and implementing workflows, protocols and procedures.