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  • Location: Oxford
  • Salary: £34000 - £38000 per annum, Benefits: pension, life insurance, health insurance, 25 days holiday
  • Job Type:Permanent

Posted 3 months ago

A truly pioneering Biotech who have developed automated mammalian cell engineering technologies and their application to accelerate the development and manufacture of Gene Therapies, CRISPR / Gene Editing and Antibody based therapeutics. Are seeking a Bioinformatician to play a key role in their R&D programmes applying complex algorithms for the analysis of large volumes of data, in particular sequencing.

Based in Oxford you will be part of a developing team that is increasing in size and influence across the business on the commercialisation of their cutting-edge technologies. Using your expertise to accelerate the discovery, development, and manufacture of cell & gene therapies. The core focus of the Scientist role is to develop and implement bioinformatics pipelines that includes Machine Learning techniques. You will be working with internal colleagues, Group Leaders, and external collaborators in this role. Please note that remote working is possible with this role.

The responsibilities of the Scientist - Bioinformatician includes:

  • Developing and implementing experimental programmes working with internal and external stakeholders

  • Making recommendations to optimise procedures and processes, with a focus on data integrity and accuracy.

  • Applying programming and scripting in languages such as R or Python to develop methods for the analysis of large datasets

  • Analysing datasets from Next Generation Sequencing

  • Applying machine learning approaches for the analysis of unique and large datasets

  • Supervising more junior members of the team.

Skills & expertise:

They are seeking a scientist with the following experience:

  • MSc or PhD in Computational Biology or Bioinformatics, or Relevant Discipline

  • Demonstrable experience of working with NGS – e.g. fastq / bed for example

  • Expertise in standard bioinformatics file types -  e.g. fasta, sam, bam

  • Scripting expertise in R or Python

  • Experience of containerization languages e.g. vitural env, conda / biconda, Bash

  • Experience of working with control software such as github or bitbucket.

Company Overview:

The company are a pioneering Biotech based on the outskirts of Oxford and are reimagining what is possible with mammalian cell engineering to accelerate the discovery, development and manufacture of cell & gene therapies. With a particular focus on the development of lentiviral, AAV and adenoviral vectors.

They have the capability to conduct robust mammalian cell engineering with their automated and informatics driven approaches means they can solve problems no one else can. They have developed advanced platforms provide market leading expertise in support of the development of gene therapies, antibody-based therapeutics and the application of CRISPR / gene editing technologies. 

They have a strong culture that is focused on scientific excellence and innovation working in a collaborative environment to ensure they continue to develop new concepts. They have a strong rewards and recognition programme ranging from on the spot rewards to recognising long term achievements. As a company they offer excellent career progression based on not only their expansion plans but also their track record for regular promotions, as well as providing training needed to be able to take the next step in your career.