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  • Location: Central London
  • Salary: £34000 - £38000 per annum, Benefits: bonus, pension, life insurance, health insurance. 28 days holiday
  • Job Type:Permanent

Posted 3 months ago

  • Sector: Clinical Operations
  • Contact: James Hume
  • Contact Email:
  • Contact Phone: 01403 216216
  • Start Date: 2021-01-07
  • Job Ref: V-46593

A pioneering company who are at the centre of the Cell & Gene Therapy sector are seeking a Scientist to join their core R&D group based in Central London.   They are recruiting for a Scientist with a background in pluripotent stem cells (PSC’s) and molecular Biology to develop, design and contribute to research programmes for the translation of pluripotent stem cell-based therapies.

The Role of Senior Scientist:

As a Senior Scientist you will be providing input into the design of and driving programmes in the laboratories which are focusing on the translation of pluripotent stem cell-based therapies.  With the focus on the development of closed and scalable commercial bioprocessing techniques.  You will be working with Senior and Lead Scientists to develop programs and then execute these in the laboratories. 

Responsibilities includes:

  • Execute lab-based R&D projects applying your knowledge of Pluripotent Stem Cells (PSC’s) to characterise and optimise expansion and differentiation processes

  • Support the translation of research-based processes into clinical manufacturing protocols.

  • Plan, write, and execute scientific protocols

  • Mentor and guide more junior team members.

  • Contribute to the design of projects, working with the Senior and Lead Scientists to establish these

This is an excellent opportunity where you will be able to apply your science in an innovative environment at the cutting edge for develop of Cell & Gene Therapies with excellent career potential.

Required Skills and Expertise:

  • PhD in relevant area is essential

  • Good knowledge of PSC biology with expertise in maintenance and differentiation essential.

  • Expertise in mammalian cell culture and analytical techniques such as flowcytometry, PCR, cell counts is essential

  • Experience of haematopoietic lineage (e.g. hematopoietic progenitor cells, lymphocytes, NK cells)is advantageous not essential

  • Experience of novel cell processing (e.g. upstream processing) is advantageous

Company Overview:

The company’s aim is to advance the cell & gene therapy sector to make the UK the place to commercialise these life changing therapies.  They have the capabilities to take a therapy from the discovery phases, across the translational gap to the clinic and then through clinical trials to launch.  Using their R&D expertise to achieve this along with their drive for innovation and continuously adopting the latest and most effective approaches.  To compliment their R&D efforts they have world class clinical operations, regulatory, health economics and market access expertise.  Added to this they have developed a unique and highly successful GMP manufacturing facility based in Stevenage where collaborators can manufacture their therapies for clinical trial and commercial use.

They have a strong culture that is focused on collaborative and innovative working to deliver these life changing therapies to patients.  As a company they offer excellent career development opportunities through their L&D programme that not only gives you the skills to advance your career but creates opportunities to take the step forwards to utilise them in a new position.  Added to this they are continuing to expand as the demand for their expertise increases and they explore new areas of the sector.