Mid/Senior Computational Drug Discovery Scientist Berkshire

Mid/Senior Computational Drug Discovery Scientist

Computational Drug Discovery Scientists use modelling and simulation to accelerate early-stage drug discovery. They design and optimize small molecules through computer-aided drug design (CADD) and structure-based modelling.

Core duties:

• Running molecular docking, dynamics, and pharmacophore modelling – Using software like Schrodinger, MOE, or OpenEye.

• Collaborating with medicinal chemistry and biology teams – Informing compound selection and SAR analysis.

• Designing virtual screening workflows – Prioritising libraries and filtering based on predicted properties (e.g., ADMET).

• Building QSAR and ML models – To predict compound activity and guide lead optimization.

• Contributing to publications and intellectual property – Supporting innovation across internal pipelines or collaborations.

Candidates typically have a PhD in computational chemistry, structural biology, or cheminformatics, with strong coding and visualization skills.​

Berkshire

The Royal County of Berkshire is a county in south east England to the west of London.    Major towns in Berkshire include Reading, Slough, Bracknell, Maidenhead, Newbury and Windsor.  The area along Thames Valley or M4 corridor which includes Reading, Bracknell and Newbury has the highest concentration of technology companies in the UK, the county is also home to numerous pharmaceutical, biotech and life sciences companies ranging from start-ups to global corporations.   For sports fans Berkshire is home to Reading town FC, London Irish RC and several famous race courses including Windsor, Newbury, Marlow and Ascot, the latter hosting the world famous Royal Meeting in June each year.

Famous people born in Berkshire:  Catherine, Duchess of Cambridge and Ricky Gervais, comedian