Mid/Senior Computational Drug Discovery Scientist Bridgend

Mid/Senior Computational Drug Discovery Scientist

Computational Drug Discovery Scientists use modelling and simulation to accelerate early-stage drug discovery. They design and optimize small molecules through computer-aided drug design (CADD) and structure-based modelling.

Core duties:

• Running molecular docking, dynamics, and pharmacophore modelling – Using software like Schrodinger, MOE, or OpenEye.

• Collaborating with medicinal chemistry and biology teams – Informing compound selection and SAR analysis.

• Designing virtual screening workflows – Prioritising libraries and filtering based on predicted properties (e.g., ADMET).

• Building QSAR and ML models – To predict compound activity and guide lead optimization.

• Contributing to publications and intellectual property – Supporting innovation across internal pipelines or collaborations.

Candidates typically have a PhD in computational chemistry, structural biology, or cheminformatics, with strong coding and visualization skills.​

Bridgend is a town 20 miles west of the capital Cardiff and 20 miles east of Swansea.

​

Bridgend is a great place to further your career in life sciences. If you are a looking for pharmaceutical jobs in Wales, scientific careers in Wales or want to discuss cell therapy, gene therapy, ATMP, medical device, technology, biotech or pharmaceutical job opportunities in Wales, give our Next Phase team a call. The Bridgend area is continuing to expand as a centre for jobs in science, process development, technology, software development, project management, informatics, quality, reg affairs and supply chain.

At Next Phase we help people find new jobs in life sciences across the UK, Europe and USA. This page lists some of the job opportunities in Wales, and if you give us a call we can also talk to you about other scientific jobs, pharmaceutical career opportunities and the latest updates in cell and gene therapy and ATMP development in the Bridgend area.