Mid/Senior Computational Drug Discovery Scientist Cambridgeshire

Mid/Senior Computational Drug Discovery Scientist

Computational Drug Discovery Scientists use modelling and simulation to accelerate early-stage drug discovery. They design and optimize small molecules through computer-aided drug design (CADD) and structure-based modelling.

Core duties:

• Running molecular docking, dynamics, and pharmacophore modelling – Using software like Schrodinger, MOE, or OpenEye.

• Collaborating with medicinal chemistry and biology teams – Informing compound selection and SAR analysis.

• Designing virtual screening workflows – Prioritising libraries and filtering based on predicted properties (e.g., ADMET).

• Building QSAR and ML models – To predict compound activity and guide lead optimization.

• Contributing to publications and intellectual property – Supporting innovation across internal pipelines or collaborations.

Candidates typically have a PhD in computational chemistry, structural biology, or cheminformatics, with strong coding and visualization skills.​

Cambridgeshire

Cambridgeshire is county in the East of England region.  Major towns and cities in Cambridgeshire include Cambridge, Peterborough and Huntingdon.  Most of Cambridgeshire is agricultural.  However, recent years have witnessed the rapid growth of a large cluster of high-tech electronics, IT, software and biotechnology businesses setting up in the area, so much so that it is now referred to as “Silicon Fen”.   Many of these high-tech businesses have grown up around the world famous Cambridge University, which is frequently ranked as one of the top universities in the world.  The city of Cambridge with its stunning architecture, museums and riverside location is a popular tourist destination.                                                                 

Famous people born in Cambridgeshire:  Clive Woodward, World Cup winning England rugby coach and Olivia Newton-John, singer