Mid/Senior Computational Drug Discovery Scientist Feltham

Mid/Senior Computational Drug Discovery Scientist

Computational Drug Discovery Scientists use modelling and simulation to accelerate early-stage drug discovery. They design and optimize small molecules through computer-aided drug design (CADD) and structure-based modelling.

Core duties:

• Running molecular docking, dynamics, and pharmacophore modelling – Using software like Schrodinger, MOE, or OpenEye.

• Collaborating with medicinal chemistry and biology teams – Informing compound selection and SAR analysis.

• Designing virtual screening workflows – Prioritising libraries and filtering based on predicted properties (e.g., ADMET).

• Building QSAR and ML models – To predict compound activity and guide lead optimization.

• Contributing to publications and intellectual property – Supporting innovation across internal pipelines or collaborations.

Candidates typically have a PhD in computational chemistry, structural biology, or cheminformatics, with strong coding and visualization skills.​

Feltham

Feltham is a town in the west London Borough of Hounslow, approximately 13 miles from central London and 2 miles from Heathrow Airport.   Due to its close proximity to Heathrow airport, one of the busiest international airports in the world, one of the largest business sectors and employers in the area is logistics.  Even before the development of Heathrow airport, Feltham had been associated with both rail and air transport for many years.  Large numbers of aircraft were manufactured in the area, particularly during World War 2, and the town was also a major centre for rail freight.  The borough of Hounslow is also a technology hub, with hi-tech companies accounting for nearly 20% of all businesses.   Although many people work locally, Feltham’s good rail and road connections into London make it a popular commuter area too.

Famous people from Feltham:  Freddie Mercury, lead singer with Queen grew up in Feltham and Jimmy Carr, comedian was born nearby.