Mid/Senior Computational Drug Discovery Scientist Reading

Mid/Senior Computational Drug Discovery Scientist

Computational Drug Discovery Scientists use modelling and simulation to accelerate early-stage drug discovery. They design and optimize small molecules through computer-aided drug design (CADD) and structure-based modelling.

Core duties:

• Running molecular docking, dynamics, and pharmacophore modelling – Using software like Schrodinger, MOE, or OpenEye.

• Collaborating with medicinal chemistry and biology teams – Informing compound selection and SAR analysis.

• Designing virtual screening workflows – Prioritising libraries and filtering based on predicted properties (e.g., ADMET).

• Building QSAR and ML models – To predict compound activity and guide lead optimization.

• Contributing to publications and intellectual property – Supporting innovation across internal pipelines or collaborations.

Candidates typically have a PhD in computational chemistry, structural biology, or cheminformatics, with strong coding and visualization skills.​

Reading

Reading is a large town located at the confluence of the river Thames and the River Kennet in Berkshire, approximately 25 miles from Oxford, 42 miles from London and 17 miles from Basingstoke.   Reading was established in the 8th century as a market town and became prosperous over the following centuries thanks to its cloth, iron works, breweries, bulbs/seed and biscuit industries.  In the 20th century the town continued to expand and is now a significant business centre and home to the UK offices of a significant number of global Pharmaceutical, Life Science and IT companies.   The town has become famous for its annual Reading Festival held over the August Bank Holiday weekend and attended by thousands of music lovers.

Famous people born in Reading: Ricky Gervais (comedian) and Kate Winslet (actress)