Senior Scientist II, PD Vector – Upstream Berkshire

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Berkshire

The Royal County of Berkshire is a county in south east England to the west of London.    Major towns in Berkshire include Reading, Slough, Bracknell, Maidenhead, Newbury and Windsor.  The area along Thames Valley or M4 corridor which includes Reading, Bracknell and Newbury has the highest concentration of technology companies in the UK, the county is also home to numerous pharmaceutical, biotech and life sciences companies ranging from start-ups to global corporations.   For sports fans Berkshire is home to Reading town FC, London Irish RC and several famous race courses including Windsor, Newbury, Marlow and Ascot, the latter hosting the world famous Royal Meeting in June each year.

Famous people born in Berkshire:  Catherine, Duchess of Cambridge and Ricky Gervais, comedian