Senior Scientist II, PD Vector – Upstream Borehamwood

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Borehamwood

Borehamwood is a town in Hertfordshire in the East of England region located approximately 12 miles north east of central London, 7 miles from Watford, 8 from St Albans and 20 from Luton.

Borehamwood’s strategic location with direct access to the M25, M1 and A1M motorways, frequent 18 minutes train service to Charing Cross and excellent connections to Heathrow, Gatwick, Luton and Stansted Airports make it a prime commuter location.  There is, however,

a  wide  range  of  businesses  in Borehamwood with  the creative  industries  and  niche  pharmaceutical companies being particularly well represented.    The world famous Elstree Studios are also located in Borehamwood; popular TV shows that are filmed at Elstree include Holby City, Who Wants to be a Millionaire and East Enders.

Famous people from Borehamwood:  Simon Cowell, reality TV judge and Marilyn, 1980’s “New Romantic” pop singer