Senior Scientist II, PD Vector – Upstream Cranleigh

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Cranleigh

Cranleigh, which is situated in Surrey in the South East Region, is reputedly the largest village in England.   Cranleigh is located approximately 50 miles from London, 8 from Guildford, 12 from Horsham and 9 from Dorking.   Although there are some light engineering companies in Cranleigh, many residents commute to London, Guildford and other larger towns.   The Beeching railway cuts meant that Cranleigh lost its station in 1965 and the nearest one is now in Chilworth, approximately 8 miles away.   Cranleigh is surrounded by beautiful open countryside and is close to Petworth House, Winkworth Arboretum and Leith Hill.

Cranleigh is famous for two main reasons.  Firstly, in 1859 it was the first place to set up a cottage hospital and secondly the head of a grinning cat is carved on an arch in the church and this is believed to have been the inspiration for Lewis Carroll's Cheshire Cat.

Famous people from Cranleigh include: Anna Botting, Sky News Presenter and W Heath Robinson, Cartoonist & Illustrator