Senior Scientist II, PD Vector – Upstream Feltham

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Feltham

Feltham is a town in the west London Borough of Hounslow, approximately 13 miles from central London and 2 miles from Heathrow Airport.   Due to its close proximity to Heathrow airport, one of the busiest international airports in the world, one of the largest business sectors and employers in the area is logistics.  Even before the development of Heathrow airport, Feltham had been associated with both rail and air transport for many years.  Large numbers of aircraft were manufactured in the area, particularly during World War 2, and the town was also a major centre for rail freight.  The borough of Hounslow is also a technology hub, with hi-tech companies accounting for nearly 20% of all businesses.   Although many people work locally, Feltham’s good rail and road connections into London make it a popular commuter area too.

Famous people from Feltham:  Freddie Mercury, lead singer with Queen grew up in Feltham and Jimmy Carr, comedian was born nearby.