Senior Scientist II, PD Vector – Upstream Hertfordshire

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Hertfordshire

Hertfordshire is a county in the south east of England, to the north of London.  Major towns and cities in Hertfordshire include Hemel Hempstead, Stevenage, Watford and St Albans. Many national and international businesses have their headquarters in the county.   Areas of particular strength in Hertfordshire include advanced engineering, logistics, life sciences and IT.  Facilities such as the Stevenage Bioscience Catalyst make Hertfordshire a very attractive proposition for pharmaceutical, biotech and life science companies.   Borehamwood is the location for the world famous The Elstree film studios at which Harry Potter, James Bond, Star Wars and other films were made as well as being the location for filming East Enders.

Famous people born in Hertfordshire: George Ezra, singer and Victoria Beckham, singer/fashion designer