Senior Scientist II, PD Vector – Upstream Reading

Senior Scientist II, PD Vector – Upstream

Senior Scientists in Upstream Process Development for Vector Production lead process design and optimisation for viral vector manufacturing, crucial for gene therapies and vaccines.

Key tasks include:

• Designing transfection or infection workflows – Using HEK293, Sf9/Baculovirus, or AAV platforms.

• Scaling up processes from bench to bioreactor – Optimising parameters such as MOI, media composition, and harvest timing.

• Writing process protocols and technical reports – Supporting internal reviews and regulatory documentation.

• Troubleshooting production challenges – Investigating yield, impurity, or cell viability issues.

• Collaborating with downstream and analytical teams – To ensure process compatibility and consistent product quality.

This role combines deep technical knowledge with problem-solving and cross-functional collaboration in GMP development settings.​

Reading

Reading is a large town located at the confluence of the river Thames and the River Kennet in Berkshire, approximately 25 miles from Oxford, 42 miles from London and 17 miles from Basingstoke.   Reading was established in the 8th century as a market town and became prosperous over the following centuries thanks to its cloth, iron works, breweries, bulbs/seed and biscuit industries.  In the 20th century the town continued to expand and is now a significant business centre and home to the UK offices of a significant number of global Pharmaceutical, Life Science and IT companies.   The town has become famous for its annual Reading Festival held over the August Bank Holiday weekend and attended by thousands of music lovers.

Famous people born in Reading: Ricky Gervais (comedian) and Kate Winslet (actress)