Analytical Development Scientist

Analytical Development Scientist

Job Title: Analytical Development Scientist
Contract Type: Permanent
Location: Central London
Salary: Competitive
Start Date: 2017-12-21
Reference: 15704+JH
Contact Name: James Hume
Contact Email:
Job Published: December 29, 2017 09:03

Job Description

James Hume is recruiting for two Analytical Development Scientists because of an increased volume of projects for the commercialisation of novel cell and gene therapies.  The company are a unique R&D organisation that focusses on the development of the industry by offering services to commercialise cell and gene therapies.  With the ability to take these across the translational gap into clinical trials.  They need an Analytical Development Scientist to support the development of Cell and Gene Therapy products with this role focussing on the characterisation of Viral Vectors.

Company Description

The company have established a centre of excellence at their Central London laboratories to support the development of cell and gene therapies through the commercialisation process. They collaborate with academic and industrial partners, who are developing novel therapies, to take these from the concept stage to the market by using cutting edge methodologies to achieve this.  They were established in 2012 with the purpose to support the growth of the cell and gene therapy industry.  Since then have gone from strength to strength because of the technical expertise they have to develop therapies from concept to market launch.  For example, they have taken therapies across a range of therapeutic areas to phase II clinical trials already.  With these moving to phase III trials they have opened a new facility in Stevenage to manufacture on a scale large enough for phase III trials and operate on a hotel concept.  They offer cutting edge technology and innovation to enable organisations to take therapies into clinical trials by providing process development, analytical development and manufacturing expertise to do so.

The Opportunity

The Analytical Development Scientist role is within the Analytical Development Department as part of their industrialisation group.  You will be working with senior and lead scientists to design and plan analytical research programmes that focus on the development of viral vectors.  They work with lentiviral, adenoviral and retroviral vectors.

They work in state of the art laboratories using a wide range of analytical techniques to develop, run, optimise and validate assays for the characterisation of viral vectors.  Then analysing the data to be submitted in reports and produce detailed protocols and SOP’s for the assay transfer internally and externally to collaborators.

Working from the bench on assigned projects you will be using your science and creative thinking to drive these forward so that results are delivered on time.  You will be leading projects from the set-up phase till close out, leading these internally by working with colleagues, from senior to junior, in the laboratory to develop the science needed to support the creation of viral vectors.  


You will be preferably be PhD level in a relevant life science with some post-doctoral or commercial experience.  You must have experience of the characterisation of viral vectors such as lentiviral, AAH, retroviral etc.  Developing, optimising and then validating the assays.

You will however need to also have experience in at least two of the following: 

  • Analytical Techniques for Viral Characterisation.
  • PCR – (RT-qPCR is advantageous)
  • Flow Cytometry – Multicolour experience is advantageous
  • DNA / RNA isolation / purification.
  • Immunoassay Development e.g. ELISA
  • Protein Arrays
  • MSD
  • Luminex

Skills such as Next Generation Sequencing, Genotyping, Mammalian Cell Culture, and Fluorescent imaging are advantageous to your application.

This is a permanent role