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Expired
  • Salary: Up to £38,000 plus excellent benefits
  • Job Type:Permanent

Posted over 6 years ago

  • Contact: James Hume
  • Contact Email: james.hume@nextphaserecruitment.com
  • Contact Phone: +44 1403 216200
  • Duration: n/a
  • Start Date: ASAP
  • Job Ref: 15529+JH
  • Analytical Development Scientist – Biotech
  • ** Multiple Vacancies Available**
  • Location: Central London
  • Salary: Up to £38,000 plus excellent benefits including bonus, 15% pension, private medical cover, life assurance plus others
  • Multiple Vacancies Created by a Continued Increase in Development Projects
  • Assay Development, Optimisation and Validation Experience Essential
Opportunity Summary

James Hume is recruiting for multiple Analytical Development Scientists because of an increased volume of development projects for the commercialisation of cutting edge, novel cell and gene therapies.  The company are a unique R&D organisation that focuses on the development of the industry by offering services to commercialise cell and gene therapies.  With the ability to take these across the translational gap into clinical trials.  With the ability to take therapies through the clinical trial process to market launch.  They need a number of analytical scientists to support the development of these therapies from concept stage into clinical trials.

Company Description


The company have established a centre of excellence at their Central London laboratories to support the development of cell and gene therapies through the commercialisation process. They collaborate with academic and industrial partners, who are developing novel therapies, to take these from the concept stage to the market by using cutting edge methodologies to achieve this.  They were established in 2012 with the purpose to support the growth of the cell and gene therapy industry.  Since then have gone from strength to strength because of the technical expertise they have to develop therapies from concept to market launch.  They offer cutting edge technology and innovation to enable organisations to take therapies into clinical trials by providing process development, analytical development and manufacturing expertise to do so.

The Role

The Analytical Scientist role is within the analytical development department as part of their industrialisation group and is one where you will be able to use your science and creativity to support the development and validation of novel cell characterisation methods.  With the purpose to support the development of new therapies.  You will be working with senior and lead scientists to design and plan analytical research programmes for each project.   In this role you will be able to use your science to contribute to these plans and then work autonomously to deliver your research. 

They work in state of the art laboratories using a wide range of analytical techniques to develop, run and optimise assays assays, including RT – qPCR, DNA / RNA isolation and purification, Flow Cytometry, and protein arrays such as MSD or Luminex.  You will run the various assays using your technical expertise to optimise and validate these.  Then analysing the data to be submitted in reports and produce detailed protocols and SOP’s fir the assay transfer internally and externally to collaborators


This is an excellent role because you will gain commercial GMP experience as well as be exposed to new techniques which will help you develop your career with this fast growing company.   

Experience

You will need to be educated to at least MSc level in a relevant life science with some academic or commercial experience.  If you have a PhD then this is advantageous to your application and if you do then you don’t have to have post doc or other experience – again this is advantageous. You must have experience developing, optimising and validating assays for this opportunity.  You will however need to also have experience in at least two of the following:
  • PCR – (RT-qPCR is advantageous)
  • Flow Cytometry – Multicolour experience is advantageous
  • DNA / RNA isolation  / purification.
  • Protein Arrays
  • MSD
  • Luminex
Skills such as Next Generation Sequencing, Genotyping, Mammalian Cell Culture, and Fluorescent imaging are advantageous to your application.

Keywords

GMP, Assay, Design, Optimisation, Validation, Dataset, Analysis, Analytical, Gene expression microarrays, high throughput PCR, high content screening, high throughput flow cytometry, next generation sequencing, multiparametric, pattern analysis, predictive modelling, power analysis, dimensional reduction, principal component analysis, QRT – PCR, nucleic acid detection, digital PCR, immunocytochemistry, morphometric analysis, epifluourescence, confocal microscopy, microarray, NGS, next generation sequencing, RT-qPCR, analytical development, DNA, RNA, tech transfer, QMS, report, cell culture, microarray, protein array, MSD, Luminex, genotyping, G – Banding, FISH, CGH, SNP, fluorescent imaging, epiflourescent, confocal microscopy, flow cytometry, primer design, cytokines.

This is a permanent role