- Analytical Scientist – Molecular Biology
- Location: Central London
- Salary: Up to £40,000 plus excellent benefits including bonus, 15% pension, private medical cover, life assurance plus others
- Excellent Opportunity to Join a Company at the Cutting Edge of Research into Cell & Gene Therapies
- Purpose: To Develop and Validate Innovative Approaches for Cell Characterisation to Support the Development of Cell Therapies
James Hume is recruiting for an Analytical Scientist with a background in Molecular Biology to join a centre of excellence for the development of cell and gene therapies based in Central London. The company’s aim is to work with their collaborators from both academia and industry to take their novel technologies from concept through the commercialisation process to launch. To further develop their research they need to recruit an Analytical Scientist to support innovative methods of cell characterisation for the development of cell therapies.
The company have established a centre of excellence at their Central London laboratories to support the development of cell and gene therapies through the commercialisation process. They collaborate with academic and industrial partners, who are developing novel therapies, to take these from the concept stage to the market by using cutting edge methodologies to achieve this. In addition to the laboratory support they are able manage the clinical trial process across all phases to product launch. They provide process development, manufacturing, analytical development, clinical, regulatory, quality, health economics and market access expertise to achieve this. So far they have successfully taken therapies through to stage II clinical trials, and were in fact the first to do so in the UK. They are now putting in place the facilities to support large phase III trials and the increasing volume of development projects. With the construction of a new facility that is to be based in Stevenage opening early next year. Regenerative medicine is one of the Government’s “eight great technologies” and the company aims to make the UK the logical choice for UK based and international partners to develop and commercialise their advanced therapies.
This role is within the analytical development department and is one where you will be able to use your science and creativity to support the development and validation of novel cell characterisation methods to support the development of new therapies. You will be working with senior and lead scientists to design and plan analytical research programmes for each project. In this role you will be able to use your science to contribute to these plans and then work autonomously to deliver your research.
They work in state of the art laboratories using a wide range of analytical techniques to develop assays, including RT – qPCR, primer design and DNA / RNA isolation & purification techniques. As well as using expression microarrays, genotyping methods for primary and other cell lines as well as Next Generation Sequencing and library construction techniques. These are examples of the types of techniques they use but not an exhaustive list.
This is an excellent role because you will gain commercial GMP experience as well as be exposed to new techniques which will help you develop your career with this fast growing company.
You will need to be educated to at least MSc level, PhD is preferred but not essential in a relevant research area which included molecular biology techniques. Specifically you will need to have experience of PCR and preferably RT – qPCR as well as techniques to isolate and purify DNA / RNA, cell culture, transcript analysis, NGS (not essential), and genotyping. If you have industrial experience then this is advantageous to your application.
GMP, Assay, Design, Optimisation, Validation, Dataset, Analysis, Analytical, Gene expression microarrays, high throughput PCR, high content screening, high throughput flow cytometry, next generation sequencing, multiparametric, pattern analysis, predictive modelling, power analysis, dimensional reduction, principal component analysis, QRT – PCR, nucleic acid detection, digital PCR, immunocytochemistry, morphometric analysis, epifluourescence, confocal microscopy, microarray, NGS, next generation sequencing, RT-qPCR, analytical development, DNA, RNA, tech transfer, QMS, report, cell culture, microarray.
This is a permanent role