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Expired
  • Location: Oxford
  • Salary: Up to £50,000 plus benefits
  • Job Type:Permanent

Posted almost 7 years ago

  • Contact: James Hume
  • Contact Email: james.hume@nextphaserecruitment.com
  • Contact Phone: +44 1403 216200
  • Duration: n/a
  • Start Date: 2017-06-28
  • Job Ref: 15486 JH
  • Job Title: Group Leader – Cell Line Development
  • Salary: Up to £50,000 D.o.E. plus benefits
  • Location: Oxford
  • Excellent Opportunity to Join a Cutting Edge Synthetic Biology Company Developing Solutions for the Cell and Gene Therapy industries.
  • An Influential Role Leading a Team of Multi Disciplinary Scientists Developing Cell Lines for the Production of Therapeutic Proteins and Viral Vectors.
Job Summary:
This is a truly exciting opportunity to join a fast developing biotech who are pioneers in the use of synthetic biology and its application to transform the discovery, development and manufacture of biologics, cell & gene therapies.  Based in state-of-the-art laboratories near Oxford they are at the cutting edge of research in this field, which has huge potential to deliver solutions for the production of complex, high value products.  They need to recruit a Group Leader who can lead a team to deliver research projects in partnership with commercial organisations, alongside internal platform development projects that are crucial to the continued growth of the company. 

The Opportunity:
The Group Leader is an influential role leading a team of multi – disciplinary scientists developing production methods for therapeutic proteins and viral vectors using mammalian cells. As the Group Leader you will be line managing a team of 8 scientists working on both internal and external research projects.  With the responsibility for their line management, performance and training & development.  Acting as their mentor to help develop their own skills and support their career progression.

Alongside the day to day management of the laboratory operations you will have engagement with external clients as a subject matter expert and Group Leader.  You will be involved in projects from the very beginning setting out the timelines, resources, milestones etc. of these and then managing them to delivery.  They operate in a matrix environment meaning you will work with other Group Leaders from the Molecular Biology, Bioinformatics, and Process Development teams on both internal and external projects.  Working together to ensure results are delivered by working in collaboration with each other to pool your resources and create solutions to problems the sector faces. 
 
They are seeking a creative scientist who can bring on board new technologies, develop new methods using their cutting edge technologies, keep up to date with sector developments to ensure they stay at the forefront of research into this exciting and fast developing sector.

Desired Skills and Experience:
They are looking for a PhD, or equivalent, qualified scientist in a relevant discipline with experience of the development of cell lines for bio production.  Alongside this you will also need to have experience of managing teams both directly and in a matrix environment.  As well as experience of overseeing the quality of work completed so that it meets regulatory requirements and company standards.  With the ability to engage with external clients to provide updates, reports and scientific expertise.

The Company
The company are at the cutting edge of the exciting field of synthetic biology after developing their unique platform which enables them to offer solutions to the discovery, development and manufacture of biologics, cell & gene therapies.  They currently offer a range of custom and platform services, specialising in DNA design, optimisation of protein and viral expression systems, and cell line development technologies. 

A strong focus is placed on R&D activities and further developing platform technologies, as supported by the recent receipt of multiple grants awards from Innovate UK.  Which will enable them to realise their potential and have a positive impact on the cell and gene therapy sectors.

Keywords
Virus, viral, viral vector, bioprocessing, upstream, downstream, GMP, in vivo, ex vivo, gene therapy, cell therapy, vector, analytical development, scale up, bioprocess, biologics, bacteria, mammalian, human, primary, cell culture, industrialisation, commercialisation, engineering, bioreactor, chromatography, filtration, separation, purification, assay, characterisation, in process, control, biochemistry, molecular biology, cell line, mammalian, cell culture, synthetic biology, flow cytometry, recombinant protein, antibody, retrovirus, lentivirus, protein expression, robot, automation, bioreactor, manage, line management, matrix, protein, therapeutic protein.