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  • Location: London, Greater London, England
  • Salary: Competitive
  • Job Type:Permanent

Posted 26 days ago

  • Sector: Translational Science
  • Contact: James Hume
  • Contact Email: james.hume@nextphaserecruitment.com
  • Contact Phone: 01403 216216
  • Start Date: 2021-08-22
  • Job Ref: V-46989
A pioneering company who are at the centre of the Cell & Gene Therapy sector are seeking a Lead Scientist to take on an influential position within their R&D Group based in 1200 m2 laboratories in Central London.  The role of Lead Scientist is to provide leadership and in-depth expertise in the process, analytical and manufacturing development of Viral Vectors.  Playing a key role in developing the strategy for the group to ensure they stay at the cutting edge of the sector by developing / or adopting the latest techniques.

As a company they have developed an end-to-end manufacturing process for AAV which they are now using to support the growth of the Cell & Gene Therapy Sector.  The Lead Scientist will take full responsibility for the management of a team and the design, planning, and execution of development programmes for AAV and Lentiviral vectors. 

Key responsibilities include:

  • Lead the development of the strategy for viral vector process development working with the CSO, MD R&D, and Head of Viral Vectors.
  • Deliver viral vector development programmes using your technical expertise and work with relevant subject matter experts.
  • Keep the group at the cutting edge of R&D by incorporating the latest developments in this area.
  • Work closely with key external and internal stakeholders to ensure programmes are fully assessed to ensure they benefit the wider industry.
Required Skills and Expertise:

  • PhD in relevant area and commercial experience within the Cell & Gene Therapy Sector.
  • Demonstrable experience of working with Viral Vectors
  • Experience of the Upstream Bioprocessing / Process Development of viral vectors
  • Experience of Cell line development
  • Experience of working with AKTA, chromatography, filtration, and other purification techniques.
  • Experience of molecular biology techniques such as flow cytometry and PCR
  • Understanding of CMC and / or GMP Ready process is desirable.
Company Overview:

The company’s aim is to advance the cell & gene therapy sector to make the UK the place to commercialise these life changing therapies.  They have the capabilities to take a therapy from the discovery phases, across the translational gap to the clinic and then through clinical trials to launch.  Using their R&D expertise to achieve this along with their drive for innovation and continuously adopting the latest and most effective approaches. 

They have a strong culture that is focused on collaborative and innovative working to deliver these life changing therapies to patients.  As a company they offer excellent career development opportunities through their L&D programme that not only gives you the skills to advance your career but creates opportunities to take the step forwards to utilise them in a new position.  Added to this they are continuing to expand as the demand for their expertise increases and they explore new areas of the sector.