- Job Title: Scientist - Antibody Discovery
- Salary: £30,000 to £40,000 plus excellent benefits including pension, life insurance, health insurance
- Location: Oxford
- An Opportunity with Great Potential because the Company are Expanding Internationally based on the Success of their Platform Technology and the Impact on the Biologics, Cell & Gene Therapy Sector.
- A Leader in the Synthetic Biology Sector, they are a Specialised CRO who Offer Services for the Discovery, Development, and Production of Biologics and Viral Vectors for Gene Therapies.
The Process Development Scientist opportunity provides the chance to join a company who are at the beginning of their expansion based on the potential of the synthetic platform technologies. Which means, if successful, this role offers career progression as they grow and work in a creative and dynamic environment. They provide DNA design, expression system optimisation, cell line development and engineering of viral vector systems to their clients using a modular based platform technology. Behind this they have further technologies that they are bringing to the market to complement the services they currently offer. They are recruiting for a Process Development Scientist to join their Process Development team as the demand for their services increases and the need to additional expertise.
The company is leading the Synthetic Biology field in the UK and its application to the discovery, development and production of biologics, especially viral vectors for the delivery of Gene therapies. What sets them apart is the potential of not just their current platform technology which enables them to provide expertise in DNA design, expression system optimisation, cell line development, and engineering of viral delivery systems. But also, their upcoming technologies they are currently commercialising and for which they have received significant funding. In addition, this has led to expansion to the US based on demand for their services.
They take a creative and entrepreneurial approach to all they do enabling you to use your science, bring your ideas to an exciting company where they are valued.
The purpose of the Scientist within the Process Development group is to lead internal and external projects in the laboratory which are focused on the generation of upstream processes for the manufacture of therapeutic proteins and viral vectors. This role is relatively senior within the laboratories working with the Group Leader to design the cell culture experimental programmes then running these in the laboratory, guiding technicians, driving these forward till their conclusion. As this is a more senior position you will have regular interaction with clients as a point of contact providing technical advice, and presenting results for example.
You will be working with small scale bioreactors, specifically AMBR 15, AMBR 250 and DASGIP, to develop and implement processes for mammalian cell lines for production. To specify and implement bioreactor systems and establish processes for clone screening and upstream process development purposes. What makes this opportunity stand out from others is the chance to use your science to generate new ideas in an environment where an innovative and engineering approach is encouraged.
Desired Skills and Experience:
They are looking for a PhD, or equivalent, qualified scientist in a relevant discipline with experience of using small scale bioreactor systems. For the development of upstream process development capabilities for mammalian cell lines for the production of therapeutic proteins and / or viral vectors. You will need to have an engineering mindset with experience of using design of experiments approach to optimise processes and procedures.