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  • Location: Oxford
  • Salary: Competitive Salary plus Benefits: life insurance, health insurance, pension, 25 days holiday
  • Job Type:Permanent

Posted about 1 month ago

  • Sector: Translational Science
  • Contact: James Hume
  • Contact Email:
  • Contact Phone: 01403 216216
  • Start Date: 2021-09-22
  • Job Ref: V-47028

A truly pioneering Biotech who are developing technologies aimed at accelerating the discovery and manufacture of Cell & Gene Therapies.  With the aim to deliver breakthroughs first so that these life changing therapies reach patients faster.   They are focused on two specific areas – Discovery and Bio Manufacture Their discovery technologies are aimed at accelerating the development of CAR – T, CRISPR, DNA Plasmid, and Capsid R&D programmes.  Their bio manufacturing expertise accelerates the development of scalable manufacture of lentiviral, AAV or adenoviral based therapeutics.

They are seeking a Scientist to join their brand new plasmid production facility with the responsibility to lead and support a range of commercial projects.  There is a focus on analytical techniques for this role to be used for scale up, characterisation and QC purposes. 

The responsibilities of Scientist includes:

  • Contribute to the design and execution of complex commercial projects

  • Performing analytical assays for characterisation and QC of plasmid DNA batches.  Such as – qPCR, ELISA etc.

  • Provide leadership to the team through the mentorship and training of less experienced colleagues.

  • Work in collaboration with colleagues in upstream & downstream process development.

  • Analysing results to direct projects and present to colleagues or collaborators.

  • Work on cross departmental projects as required.

They are seeking a scientist with the following experience:

  • MSc or BSc with demonstrable relevant lab experience or PhD in relevant discipline.

  • Experience in QC of Plasmid DNA, preferably in a commercial environment.

  • Experience in the use of standard molecular cloning techniques including PCR, restriction digestion, agarose gel electrophoresis, and DNA ligations for example.

  • Experience in the use of analytical assays such as ELISA.

  • Understanding of biological systems / biopharmaceutical production / biochemical molecule interactions.

  • Experience of working in a regulated environment is advantageous nut not essential

  • If you have GMP experience this is advantageous but not essential.

Company Overview:

The company are a pioneering Biotech based on the outskirts of Oxford and Biotech who are developing technologies aimed at accelerating the discovery and manufacture of Cell & Gene Therapies.  Their discovery technologies help develop CAR – T, T – Cell, CRISPR, Antibody Discovery, and Capsid R&D programmes to aid their translation to the clinic.  Their manufacturing expertise aims to accelerate the development of scalable manufacture of lentiviral AAV or adenoviral based therapeutics.

They have a strong culture that is focused on scientific excellence and innovation working in a collaborative environment to ensure they continue to develop new concepts.  They have a strong rewards and recognition programme ranging from on-the-spot rewards to recognising long term achievements.  As a company they offer excellent career progression based on not only their expansion plans but also their track record for regular promotions, as well as providing training needed to be able to take the next step in your career.