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  • Location: London, Greater London, England
  • Salary: Competitive
  • Job Type:Permanent

Posted about 1 month ago

  • Sector: Translational Science
  • Contact: James Hume
  • Contact Email:
  • Contact Phone: 01403 216216
  • Start Date: 2021-07-01
  • Job Ref: V-46919

A pioneering company who are at the centre of the Cell & Gene Therapy sector are seeking a Senior Scientist to join their core R&D group based in Central London.   They are recruiting for a Scientist with a background in Analytical Development for the characterisation & process development of their novel therapies.  Applying your expertise to provide insights and understanding to support the development and manufacture of ATMP’s.

The Role of Scientist:

 As a Senior Scientist you will be leading a team of analytical scientists who are responsible for performing analytical characterisation of products to support process development.  As the Senior Scientist you will be suing your expertise to develop, optimise, troubleshoot novel assays.  Additionally, you will be contributing to the design of R&D programmes from an analytical perspective.

Responsibilities includes:

  • Manage and lead an analytical characterisation team.  Applying your knowledge to drive tjhier day to day activities and training.

  • Contribute to the design and execution of assay qualification using your expertise,.

  • Lead the training of team members and the standardisation of assays to support manufacture. 

  • Responsible for sample management activities, data revision and prelease ot process development scientists.

  • Work in collaboration with the data scientist teams for the analysis of data.

  • Work in collaboration with process development, analytical and automation scientists on cutting edge R&D projects.

  • Record and communicate analytical data in publications, scientific reports, posters and presentations to colleagues and external collaborators.

  • Assays used – Flow Cytometry, PCR (ddPCR / qPCR), HPLC and ELISA.

This is an excellent opportunity where you will be able to apply your science in an innovative environment at the cutting edge for develop of Cell & Gene Therapies with excellent career potential.

Required Skills and Expertise:

  • PhD or MSc or BSc in relevant area with additional experience.

  • Experience in the development and execution of analytical assays for product characterisation

  • Experience in at least two of the following assays:

        • qPCR and / or ddPCR

        • ELISA

        • Flow Cytometry

        • HPLC

        • Product Impurity Characterisation.

  • Expeirence of product release is advantageous but not essential.

  • Experience of leading / supervision / management of people advantageous.

Company Overview:

The company’s aim is to advance the cell & gene therapy sector to make the UK the place to commercialise these life changing therapies.  They have the capabilities to take a therapy from the discovery phases, across the translational gap to the clinic and then through clinical trials to launch.  Using their R&D expertise to achieve this along with their drive for innovation and continuously adopting the latest and most effective approaches.  To completement their R&D efforts they have world class clinical operations, regulatory, health economics and market access expertise.  Added to this they have developed a unique and highly successful GMP manufacturing facility based in Stevenage where collaborators can manufacture their therapies for clinical trial and commercial use.

They have a strong culture that is focused on collaborative and innovative working to deliver these life changing therapies to patients.  As a company they offer excellent career development opportunities through their L&D programme that not only gives you the skills to advance your career but creates opportunities to take the step forwards to utilise them in a new position.  Added to this they are continuing to expand as the demand for their expertise increases and they explore new areas of the sector.